What condition can lead to ligamentous laxity in individuals with Down syndrome?

Ligamentous laxity in individuals with Down syndrome is primarily associated with the genetic and structural aspects of the condition itself. Down syndrome, caused by the presence of an extra copy of chromosome 21, often results in various skeletal abnormalities and connective tissue disorders. This genetic factor can lead to an inherent laxity in the ligaments, which is a hallmark of the condition.

Individuals with Down syndrome are particularly prone to developing issues such as atlantoaxial instability, which can further exacerbate symptoms related to ligamentous laxity. The laxity can impact joint stability, leading to a greater risk of injuries and other orthopedic issues in this population.

While the other conditions listed have their own associations with joint and ligament health, they do not specifically account for the genetic predisposition to ligamentous laxity seen in individuals with Down syndrome.