Which of the following is a primary outcome measure used with Down syndrome?

The Gross Motor Function Measure (GMFM) is specifically designed to assess changes in gross motor function in children with Down syndrome and other conditions affecting motor skills. It evaluates a child's ability to perform various gross motor tasks and is sensitive to detecting changes over time, making it particularly useful for tracking developmental progress in this population.

The GMFM is structured around specific tasks that align with typical motor development milestones, allowing for a focused assessment of physical capabilities. This tool supports clinicians and researchers in determining the effectiveness of interventions, making it a primary outcome measure for children with Down syndrome.

In contrast, the other options, while valuable in their respective contexts, are not primarily focused on the unique motor function challenges faced by children with Down syndrome. For instance, WeeFIM assesses functional independence in self-care and mobility across various disabilities, Brigance is more comprehensive in assessing developmental skills across multiple domains, and ASQ (Ages and Stages Questionnaire) targets developmental screening for children generally rather than focusing specifically on gross motor function.